Clinical Development Medical Director (Nephrology)

Role Overview 

We are seeking an experienced and mission-driven Medical Director to lead and support clinical programs in nephrology, with a focus on rare or immune-mediated kidney diseases. This role is ideal for a physician-scientist who thrives in a small biotech environment where agility, cross-functional collaboration, and scientific leadership are essential. The Medical Director will play a key role in advancing Jade’s pipeline through clinical development. This newly created position will report to the Executive Medical Director of Clinical Development. This is a fully remote role and will require some travel.

Key Responsibilities 

• Clinical Development

  • Lead the design, execution, and oversight of clinical trials in nephrology, including protocol development, study monitoring, and data interpretation.
  • Serve as Medical Monitor for ongoing trials, ensuring patient safety and scientific integrity.
  • Collaborate with clinical operations, regulatory, and biometrics teams to ensure trial success and compliance.
  • Educate and advise clinical sites/investigators to support enrollment and optimal study conduct, including presenting at investigator meetings and/or site initiation visits, and serving as the medical point of contact for site staff questions about patient eligibility, and providing input into patient safety assessment and management
  • Provide medical expertise and support to external partners, vendors, and contractors as required to ensure smooth program execution
  • Communicate effectively, orally and in writing, with internal and external stakeholders regarding the assigned clinical program, including the CMO, CEO, external medical experts and others.

  Regulatory and Scientific Contributions

  • Contribute to the preparation of regulatory documents (INDs, NDAs, briefing documents, etc.).
  • Support interactions with regulatory authorities and ethics committees.
  • Stay current with scientific literature and competitive landscape in nephrology and related fields.

  Cross-Functional Collaboration

  • Partner with translational science, biomarker, and commercial teams to align clinical strategy with broader company goals.
  • Provide medical input into lifecycle planning and early market preparation.

  Stakeholder Engagement

  • Begin building relationships with key opinion leaders (KOLs), investigators, and advocacy groups in nephrology.
  • Represent the company at scientific meetings, advisory boards, and industry events.

Qualifications 

• MD (or equivalent medical degree); board certification in nephrology strongly preferred.
• 3+ years of experience as a nephrologist in academia or industry, and/or experience in nephrology clinical trials or rare disease programs.
• Experience in clinical trial design, execution, and medical monitoring.
• Strong clinical judgment, scientific rigor, and regulatory knowledge.
• Ability to work independently and thrive in a fast-paced, matrixed environment.
• Ability to manage multiple projects simultaneously and prioritize effectively in a fast-paced environment
• Strong analytical, problem-solving, and decision-making skills
• Excellent communication and interpersonal skills with the ability to influence and motivate cross-functional teams, manage a diverse set of stakeholders, and work closely with team leaders
• High ethical standards and impeccable integrity
• Exercise sound judgment in managing complex, confidential, and regulated information.

Position Location 

This is a remote role; periodic travel to scientific conferences, sites, team and company events is required.

The anticipated salary range for candidates for this role is $270,000-$300,000. The final salary offered will depend on several factors, which may include, but not limited to, relevant years of experience, educational background, and geography.